Montenegro, IvánIvánMontenegroAlejandro Madrid2025-12-072025-12-072018-04-0510.1080/14786419.2018.14608282-s2.0-85045058415https://cris-uv-2.scimago.es/handle/123456789/7475WOS:000467764700021A series of novel dihydrochalcone derivatives 2-7 were synthesized from dihydroisorcordoin 1 which was isolated from the aerial parts of Adesmia balsamica. The structures of all compounds were confirmed by ¹H NMR, ¹³C NMR, and HRMS. Their anti-oomycete activity was evaluated in vitro against Saprolegnia parasitica and Saprolegnia diclina. Some of the newly synthesized compounds exhibited better anti-oomycete activities at low values compared with bronopol and fluconazole as positive controls. Among them, compound 7 exhibited strong activity, with minimum inhibitory concentration and minimum oomyceticidal concentration values of 75 and 100 μg/mL, respectively.enacceso restringidoAnalytical ChemistryBiochemistryChemistry, AppliedChemistry, MedicinalOrganic ChemistryPlant Sciencearticle