Case report: inhaled milrinone in pulmonary hypertension [milrinona inhalada en hipertensión pulmonar: a propósito de un caso]

Introduction: Pulmonary hypertension (PH) is a disease that is characterized for an elevated pressure in the pulmonary artery and an increased pulmonary vascular resistance (PVR).Inhaled milrinone has demonstrated acting as a selective pulmonary vasodilator, being a useful tool for the treatment of patients with PH in the perioperative.Materials and Methods: We report a successful case of inhaled milrinone in PH in cardiovascular surgery.The patient signed the informed consent for this report.Discussion: Patients with PH has increased risk of perioperative complications (mortality as far as 37-90%) The management with intravenous vasodilators is frequently limited because of secondary effects of vasodilation and hypotension affecting the myocardial perfusion pressure.Milrinone is an inodilator that acts as an inhibitor of the phosphodiesterase III.Wang et al., and posterior studies have demonstrated that administered by inhalation it acts as a selective pulmonary vasodilator and inotrope, with a minor systemic effect.Conclusion: Inhaled milrinone have demonstrated to be a useful drug to lower PH, PVR and to enhance inotropism without deleterious systemic effects.Wide availability, lower costs and ease of administration make you think as it could be an ideal tool for perioperative management in patients with PH.There are still more studies to define it´s potentials.rESUMEN Introducción: La hipertensión pulmonar (HTP) es una enfermedad caracterizada por la elevación de las presiones de arteria pulmonar (PAP) y un aumento de la resistencia vascular pulmonar (RVP).La milrinona inhalada ha demostrado actuar como un vasodilatador pulmonar selectivo siendo una herramienta útil en el manejo de los pacientes con HTP en el perioperatorio.Materiales y Métodos: Reportamos un caso exitoso de milrinona inhalada en HTP en ciru-