Rainbow Trout ( Oncorhynchus Mykiss) Proteins As A Source Of Antioxidant Peptides With Promising Anticancer Activity

Fish production worldwide is aimed at muscle consumption, and this industry discards around 60 % of the fish in undervalued by-products. A widely consumed commercial species is the rainbow trout (O. mykiss), which has a consumption presence among commercial fish of 17 %. This makes it a significant species due to the amount of waste obtained after consumption. In addition, the protein content of muscle and by-products is relevant, as it is often a source of encrypted bioactive peptides, which can be released by hydrolytic mechanisms, such as enzymatic digestion, in vitro digestion, and microbial fermentation. Several studies have proved the bioactivity of peptides obtained from fish species that contain amino acid sequences with properties that interest human health. This article reviews the protein composition, the mechanism for obtaining peptides, action ways of antioxidant peptides, in silico sequences from the BIOPEP database, and their potential anticancer activity, contrasting with discoveries in other species and emphasizing the potential of O. mykiss proteins as a source for obtaining antioxidant peptides with anticancer capacity.